Co-segregation Analysis 
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This “Co-segregation analysis website” enables you to calculate the likelihood ratio of a BRCA1 or BRCA2 sequence variant for being deleterious.
Use of Co-segregation analysis
Select ped file: help
                              (leave blank to test with the example1.ped file)  
Select gene:

Analysis Summary

This is the first version of the website. If you have general comments or suggestions please contact Maaike Vreeswijk (Department of Human Genetics, Leiden University Medical Center, The Netherlands). Your input is highly appreciated.
For specific questions (e.g. related to the ped files) contact Quinta Helmer.
For questions or comments concerning the web interface please contact H.J. van der Wijk.

We have used all reasonable efforts to ensure that the information displayed on these pages is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising out of any inaccuracies or omissions. Individuals, organizations and companies which use this program do so on the understanding that no liability whatsoever either direct or indirect shall rest upon the Leiden University Medical Center (LUMC) or any of their employees or agents for the effects of any product, process or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.